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New Engineering Technology Innovation Enables 3D Printing of Small Multilevel Microfluidic Devices with Patent-Pending Features


Assistant Professor Huachao Mao and his team at Purdue University have developed a groundbreaking method for creating microfluidic devices as small as 10 microns deep and 100 microns wide. These devices are essential for rapid and accurate analysis of small volumes of materials in various fields such as biomedical research, environmental testing, and manufacturing.

The patented innovation uses vat photopolymerization (VPP) technology, which allows for the direct fabrication of highly transparent microfluidics with narrow channels. By incorporating liquid crystal display (LCD) technology, Mao and his team have achieved higher resolution and improved efficiency in the fabrication process.

These microfluidic devices have wide-ranging applications, including cancer cell analysis, drug screenings, single-cell isolation, and point-of-care diagnostics. They offer significant advantages over traditional fabrication methods, which are costly and time-consuming, requiring high-end equipment and cleanroom environments.

The research conducted by Mao and his team in Purdue Polytechnic’s Additive and Intelligent Manufacturing Lab has the potential to revolutionize biomedical research and improve the accuracy and speed of diagnostic tests. Their work is highlighted in a recent article by Purdue Research Foundation’s Steve Martin, showcasing the groundbreaking impact of their innovative method for creating microfluidic devices.

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