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Researchers use genetic modification to create white-haired wolves resembling the extinct dire wolf


Colossal Biosciences has genetically engineered three wolf pups to resemble extinct dire wolves, a species that went extinct over 10,000 years ago. The pups have traits of dire wolves, such as long white hair and muscular jaws, and are on track to reach 140 pounds at maturity. The researchers used CRISPR technology to genetically modify cells from a living gray wolf and create the engineered pups.

While the pups may physically resemble dire wolves, they may not learn their natural behaviors such as hunting from wild parents. However, Colossal also reported cloning four red wolves from wild blood samples to help save the critically endangered species. This process could have wider conservation applications as it is less invasive compared to other cloning techniques.

Scientists not involved in the research have expressed some skepticism about the project’s ability to fully revive extinct species and restore their ecological functions in modern landscapes. While Interior Secretary Doug Burgum praised the work as a scientific wonder, there are limitations to bringing back extinct species.

Overall, the project to engineer wolves and clone red wolves has garnered attention for its potential conservation applications but also raises questions about the ethical, ecological, and practical aspects of resurrecting extinct species.

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